ADCY2 polyclonal antibody
产品名称： ADCY2 polyclonal antibody
英文名称： ADCY2 polyclonal antibody
产品编号： PAB2595
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of ADCY2.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human ADCY2.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Ammonium sulfate precipitation
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:50-100)
Immunohistochemistry (1:10-50)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Molecular genetics of successful smoking cessation: convergent genome-wide association study results.
Uhl GR, Liu QR, Drgon T, Johnson C, Walther D, Rose JE, David SP, Niaura R, Lerman C.Arch Gen Psychiatry. 2008 Jun;65(6):683-93.
- 2.
- Characterization of the human adenylyl cyclase gene family: cDNA, gene structure, and tissue distribution of the nine isoforms.
Ludwig MG, Seuwen K.J Recept Signal Transduct Res. 2002 Feb-Nov;22(1-4):79-110.
- 3.
- Expression and regulation of adenylyl cyclase isoforms in the human adrenal gland.
Cote M, Guillon G, Payet MD, Gallo-Payet N.J Clin Endocrinol Metab. 2001 Sep;86(9):4495-503.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of ADCY2 polyclonal antibody (Cat # PAB2595) in Jurkat cell line lysates (35 ug/lane). ADCY2 (arrow) was detected using the purified polyclonal antibody (1 : 60 dilution).
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human lung carcinomareacted with ADCY2 polyclonal antibody (Cat # PAB2595), which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.
This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Entrez GeneID:
- 108
- Protein Accession#:
- NP_065433;Q08462
- Gene Name:
- ADCY2
- Gene Alias:
- AC2,FLJ16822,FLJ45092,HBAC2,KIAA1060,MGC133314
- Gene Description:
- adenylate cyclase 2 (brain)
- Omim ID:
- 103071
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the G protein beta and gamma subunit complex. [provided by RefSeq
- Other Designations:
- 3',5'-cyclic AMP synthetase,ATP pyrophosphate-lyase,adenylate cyclase 2,adenylate cyclase II,adenylyl cyclase 2,type II adenylate cyclase
- Interactome
