Anti-MAP2K2 Polyclonal Antibody

品牌：solarbio | 货号：K001631P

商品货号：	商品品牌：	规格	基本售价：	选择规格
K001631P-50ul	solarbio	50ul	960.00元
K001631P-100ul	solarbio	100ul	1600.00元

英文名称 Anti-MAP2K2 Polyclonal Antibody
别名 CFC4;MAPKK2;MEK2;MKK2;PRKMK2
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量 44kDa
Gene ID 5605
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, 
pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human MAP2K2
性状 液体
Public 
Immunogen 
Range A synthetic peptide of human MAP2K2
Subcellular 
Locations Cytoplasm Membrane Peripheral membrane protein
Swiss Prot P36507
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene is a dual specificity 
protein kinase that belongs to the MAP kinase kinase 
family. This kinase is known to play a critical role in 
mitogen growth factor signal transduction. It 
phosphorylates and thus activates MAPK1/ERK2 and 
MAPK2/ERK3. The activation of this kinase itself is 
dependent on the Ser/Thr phosphorylation by MAP 
kinase kinase kinases. Mutations in this gene cause 
cardiofaciocutaneous syndrome (CFC syndrome), a 
disease characterized by heart defects, mental 
retardation, and distinctive facial features similar to 
those found in Noonan syndrome. The inhibition or 
degradation of this kinase is also found to be involved 
in the pathogenesis of Yersinia and anthrax. A 
pseudogene, which is located on chromosome 7, has 
been identified for this gene.

英文名称	Anti-MAP2K2 Polyclonal Antibody
别名	CFC4;MAPKK2;MEK2;MKK2;PRKMK2
应用	WB IHC
稀释比例	WB 1:500-2000. IHC 1:50-200.
交叉反应	Human Mouse Rat
蛋白分子量	44kDa
Gene ID	5605
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	A synthetic peptide of human MAP2K2
性状	液体
Public Immunogen Range	A synthetic peptide of human MAP2K2
Subcellular Locations	Cytoplasm Membrane Peripheral membrane protein
Swiss Prot	P36507
克隆类型	Polyclonal Antibody
背景资料	The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene.