UBE2L6 polyclonal antibody
产品名称： UBE2L6 polyclonal antibody
英文名称： UBE2L6 polyclonal antibody
产品编号： PAB3896
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of UBE2L6.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human UBE2L6.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:10-50)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Mechanism for ubiquitylation of the leukemia fusion proteins AML1-ETO and PML-RARalpha.
Kramer OH, Muller S, Buchwald M, Reichardt S, Heinzel T.FASEB J. 2008 May;22(5):1369-79. Epub 2007 Dec 11.
- Applications
- Western Blot (Cell lysate)
- The UBE2L6 polyclonal antibody (Cat # PAB3896) is used in Western blot to detect UBE2L6 in HL-60 cell lysate.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with UBE2L6 polyclonal antibody (Cat # PAB3896) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Entrez GeneID:
- 9246
- Protein Accession#:
- NP_004214;O14933
- Gene Name:
- UBE2L6
- Gene Alias:
- MGC40331,RIG-B,UBCH8
- Gene Description:
- ubiquitin-conjugating enzyme E2L 6
- Omim ID:
- 603890
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- retinoic acid induced gene B protein,ubiquitin carrier protein,ubiquitin-protein ligase
- Gene Pathway